No. |
Author |
Title |
Journal |
1 |
Hiroyuki Togawa, Takashi Okubo, Kazuki Horiuchi, Takao Yamaguchi, Elisa Tomita-Sudo, Tomoka Akita, Junji Kawakami, Satoshi Obika |
Separation of the diastereomers of phosphorothioated siRNAs by anion-exchange chromatography under non-denaturing conditions |
Journal of Chromatography A, 1721, 464847(2024) |
2 |
Tomoka Akita, Elisa Tomita-Sudo, Shin Itoh, Nae Sakimoto, Takeshi Masuda, Akifumi Nakamura, Yoshiyuki Onishi, Makoto Koizumi and Junji Kawakami |
Not all 2',4'-bridged modifications stabilize DNA/RNA duplexes |
Nucleosides, Nucleotides & Nucleic Acids, 42, 43, 57-64(2024) |
3 |
Kaoru Karasawa, Eva Duchoslav, Lyle Burton, Junji Kawakami, and Takashi Baba |
Sequencing of Morpholino Antisense Oligonucleotides Using Electron Capture Dissociation Mass Spectrometry |
Analytical Chemistry, 95, 16352-16358(2023) |
4 |
Takahiro Yaguchi, Misaki Kameno, Hirofumi Taira, and Junji Kawakami |
Mitochondrial Dynamics of Bcl-2 Family Proteins during 17-β-Estradiol-Induced Apoptosis Correlate with the Malignancy of Endometrial Cancer Cells |
Biochemistry, 62, 3041-3049(2023) |
5 |
Kenji HIROSE, Tokuyuki YOSHIDA, Maki TERASAKI, Hiroshi SEZAKI, Kaoru KARASAWA, Noriyuki IWASAKI, Kentaro TAKAHARA, Naomi TAKIGUCHI, Mitsuaki SEKIGUCHI, Hirokazu NANKAI, Emi SAITO, Hideaki SATO, Takashi OSAWA, Takao YAMAGUCHI, Kosuke ITO, Junji KAWAKAMI, Satoshi OBIKA, and Takao INOUE |
Comparison of Analysis Data of Model Oligonucleotide Therapeutics Obtained with Different Types of Liquid Chromatograph- Mass Spectrometers |
Pharmaceutical and Medical Device Regulatory Science, 54, 439-454(2023) |
6 |
瀬崎浩史、内藤厚子、林明生、川上純司、井上貴雄、山口卓男、小比賀聡 |
LC/MSを使用したオリゴ核酸の不純物分析 |
Medical Science Digest, 49, 780-782(2023) |
7 |
秋田智香、冨田恵麗沙、川上純司 |
修飾核酸 |
CLINICAL NEUROSCIENCE, 41, 639-642(2023) |
8 |
川上純司 |
日本発の核酸医薬を世界に向けて |
SCAS NEWS, 2023-I, 1-2(2023) |
9 |
冨田恵麗沙、秋田智香、川上純司 |
核酸医薬品と核酸化学 |
核酸医薬品のCMC管理戦略 −品質評価・不純物管理−, 31-54(2022) |
10 |
川上純司 |
製造委託の際に知っておきたい核酸医薬の特性 −品質と安全性評価面を中心に |
Pharm Tech Japan, 38, 2017-2022(2022) |
11 |
Toshiyuki Goto, Shuhei Torii, Aoi Kondo, Kazumasa Kanda, Junji Kawakami, Yosky Kataoka and Takahito Nishikata |
Actin Filament in the First Cell Cycle Contributes to the Determination of the Anteroposterior Axis in Ascidian Development |
J. Dev. Biol, 10, 10(2022) |
12 |
秋田智香、川上純司 |
核酸医薬の化学 総論 −修飾核酸と機能評価 |
実験医学,, 39, 2716-2722(2021) |
13 |
川上純司 |
アンチセンス核酸のメカニズム |
核酸科学ハンドブック, 508-511(2020) |
14 |
Daichi Kawano, Zhengzheng Liao, Jing Nie, Akira Date, Eduardo Perez, Jose Fernandez, Corey Webb, Kristen Huber, Jeffry B. Stock, Junji Kawakami, Zihua Fu |
Efficacy of fermented extract obtained from multiple-processed fermentation technology of thermophilic bacteria and yeast |
Journal of Japanese Cosmetic Science Society, 44, 194-202(2020) |
15 |
Md Ariful Islam, Aki Fujisaka, Junji Kawakami, Takao Yamaguchi and Satoshi Obika |
Different reactivity of Sp and Rp isomers of phosphorothioate-modified oligonucleotides in a duplex structure |
Bioorg. Med. Chem. Lett., 30, 127166(2020) |
16 |
Miho Takagi-Sato, Koji Morita, Yoshiyuki Onishi, Yuuka Watahiki, Taku Ishigaki, Tomoka Akita, Erisa Tomita, Junji Kawakami and Makoto Koizumi |
An improved synthesis of 2'-O,4'-C-ethylene nucleic acid (ENA) and thermodynamic studies of duplex formation containing the guanosine ENA unit |
Nucleosides, Nucleotides and Nucleic Acids, 39, 838-852(2020) |
17 |
川上純司 |
アンチセンス核酸医薬の作用機序 |
医薬品開発における中分子領域(核酸医薬・ペプチド医薬)の開発戦略, 13-24(2019) |
18 |
Takenori Shimo, Keisuke Tachibana, Yuki Kawawaki, Yuuka Watahiki, Taku Ishigaki, Yusuke Nakatsuji, Takashi Hara, Junji Kawakami and Satoshi Obika |
Enhancement of exon skipping activity by reduction in the secondary structure content of LNA-based splice-switching oligonucleotides |
Chem. Commun., 55, 6850-6853(2019) |
19 |
Koji Nagahama, Kenta Iseda, Daichi Kawano, Junji Kawakami |
Quantitative relationship between chemical properties and bioactivities of anti-microRNA oligonucleotides targeted to tumor-associated microRNA-21 |
Biochimie, 137, 124-131(2017) |
20 |
K. Nagahama, T. Utsumi, T. Kumano, S. Maekawa, N. Oyama, J. Kawakami |
Discovery of a new function of curcumin which enhances its anticancer therapeutic potency |
Scientific Reports, 6, 30962(2016) |